Bupropion hydro­bromide propanol hemisolvate

نویسندگان

  • Min Liu
  • Xiu-Rong Hu
  • Jian-Ming Gu
  • Gu-Ping Tang
چکیده

The title compound {systematic name: N-[1-(3-chloro-phen-yl)-1-oxopropan-2-yl]-tert-butanaminium bromide propanol hemisolvate}, C(13)H(19)ClNO(+)·Br(-)·0.5C(3)H(8)O, crystallizes with two independent bupropion hydro-bromide ion pairs and a solvent 1-propanol mol-ecule in the asymmetric unit. In both mol-ecules, the expected proton transfer from HBr to the amino group of the bupropion mol-ecule is observed, and intra- and inter-molecular N-H⋯Br hydrogen-bond inter-actions are formed. These inter-actions link the mol-ecules into hydrogen-bond dimers. The side chains of the two cations have slightly different orientations. The 1-propanol solvent mol-ecule is linked to a bromide ion by an O-H⋯Br hydrogen bond.

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عنوان ژورنال:

دوره 67  شماره 

صفحات  -

تاریخ انتشار 2011